From MedicalNewToday.com --
University of Ottawa medical researchers have discovered a mutation in a gene that is widely considered to be the major controller of energy levels in our bodies. The discovery has significant implications for people suffering from diabetes and for endurance athletes.
This study focused on the gene for AMPK (adenosine monophosphate-activated protein kinase), which controls the amount of energy in our cells by becoming active when fuel stores start to deplete, such as during exercise. The mutation discovered in individuals from two unrelated families caused a doubling of AMPK activity in muscle during rest, mimicking a state of exercise.
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The significance of this study is that "the mutation produces a decrease in the storage in muscle of fat and an increase in muscle glycogen."
Comments: Now of course, pharmaceutical companies will try to create and test a drug that could mimick this condition for the sake of people wanting to lose weight, and for those who have Type II diabetes. Not that this is a bad thing, but educating the public about the importance of a healthy diet and plenty of exercise would go much further in reducing the need for treatment of obesity and Type II diabetes. Athletes may find a drug that creates such condition a plus, especially an endurance athlete -- i.e. Tour de France? -- or blood doping may already be doing the job. We need to stop looking for the easy short cuts and start doing the sensible thing. Or have we lost all common sense?
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